Follow Us on Facebook Follow Us on Twitter Add Us on Google+
Follow Us
Store Finder  Become a Dealer / Affiliate Store Finder  Store Finder chat  Live Chat Your Account  Your Account View Cart  View Cart
 
UltimatePestRepeller.com
As Seen on TV
Call 1-800-657-8214
24 hours / 7 days a week!
 
Pest Repeller 45 Day Money Back Guarantee
Location:
Stop bugs and insects electronic pest repellers   Looking to repel a specific pest from your home or office? Use our Pest Control Guide below!

Ants I Bats I Bed Bugs I Beetles I Birds I Centipedes I Crickets I Deer I Earwigs I Fleas I Insects I Mice I Mites I Mosquitoes I Raccoons I Rats I Reptiles I Roaches I Rodents I Scorpions I Silverfish
 

University Case Study Involving Ultrasound-induced Defense Reactions in Mice

©2011 American College of Neuropsychopharmacology


"Severe Serotonin Depletion after Conditional Deletion of the Vesicular Monoamine Transporter 2 Gene in Serotonin Neurons: Neural and Behavioral Consequences"

Summary: In an aversive ultrasound-induced defense paradigm, mice displayed a major increase in “wild” escape-like behaviors. Study Keywords include depression; anxiety; defense behaviors. (Page 1)

Mice were tested for their innate fear reactions to a train of ultrasonic stimuli/us. Animals were placed one per cage for at least 1 week before testing. In brief, 100 ms frequency sweeps between 17 and 20 kHz, 85 dB, alternately ON 2 seconds and then OFF 2 seconds for 1 min were delivered into the home cage after a 3-min baseline period. Flight reactions triggered during ON periods were measured as the number of running events from one side of the cage to the other followed by behavioral arrest. The percentage time “freezing” to the ultrasonic stimuli was quantified by sampling events of complete immobility (except respiration) every 4 seconds during the OFF period. These defense behaviors were measured from a video file by an observer unaware of mouse genotype. (Page 3)

This diagram shows the Inverse relationship between brain tissue levels of 5-HT and aversive ultrasound-induced flight behaviors in mice. (a) There was an enhancement of flight behaviors in reaction to the aversive ultrasound (1 min fast sweep 17–20 kHz, 85 dB) in mice compared with control mice, which was reversed by a chronic treatment with pargyline. (Page 9)

View Full Case Study

Refrence: ©Neuropsychopharmacology (2011)
Nicolas Narboux-Nême, Corinne Sagné, Stephane Doly, Silvina L Diaz, Cédric B P Martin, + et al.
Neuropsychopharmacology 36, 2538-2550 doi:10.1038/npp.2011.142

Good Life Pest Control Products
Goodlife
Good life pest repellers
authorize.net
Click to verify BBB accreditation and to see a BBB report.
PayPal Verified    
 
Good Life Pest Control Products
Credit Cards Accepted